In July 2007, a federal district court struck down several local ordinances enacted by the city of Hazleton, Pennsylvania, which had attempted to regulate the employment of illegal immigrants. Hazleton’s efforts garnered national attention, and their ordinances served as a model for similar local immigration ordinances enacted in Beaufort County, South Carolina. This Comment examines the district court’s opinion in Lozano v. City of Hazleton, which addressed in particular the constitutional issues of preemption, due process and equal protection as they relate to local immigration regulations. This Comment then compares Beaufort County’s ordinance with Hazleton’s ordinance to determine whether Beaufort County’s attempts at regulating immigration will survive the constitutional challenges examined in Lozano.